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This editorial paper in British Medical Journal discusses how persistent stress levels in British doctors over the last 20 years. Organizational and individual ramifications of stressors, particularly errors in medicine, are discussed. Firth-Cozens underscores the need for a systematic approach to combating organizational stressors through primary preventative interventions (i.e. teamwork, leadership training, career counseling, education about error). If and when these fall short, secondary prevention (i.e. coaching, psychotherapy, or alcohol/drug treatment) is recommended.